MODIFICACIÓN DE LOS NIVELES SÉRICOS DE GRELINA EN MUJERES CON OBESIDAD SIMPLE SOMETIDAS A ACTIVIDAD FÍSICA AERÓBICA CONTROLADA Y DIETA HIPOCALÓRICA

Abstract

The problem of obesity is complicated by multiple factors, since it is the most common metabolic disorder in Mexico, because it has an influence on the quantity and quality of life, ie, has many complications that are largely responsible for increased morbidity and mortality. Ghrelin is a hormone involved in weight control by increasing or decreasing it. If this hormone rises, relative intake increases the body can lose its ability to control the metabolism of calories. The aim of this study was to determine whether physical activity is more controlled and customized effects of a hypocaloric diet on ghrelin levels in women with simple obesity over a period of twelf weeks. Material and methods. We performed an intervention study deliverables, prospective, comparative study. Were subjected to hypocaloric diet and aerobic physical activity controlled, is formed 2 groups of study of n = 16. The first group was subjected to low-calorie diet and the second group controlled aerobic exercise for 12 weeks. Values were determined by ghrelin serum ELISA study at the beginning and end of study. For statistical analysis we applied the descritive stadistic, Shapiro-Wilk test and COVARIANZA for correlation for variables. Results. In the two groups were significant changes in weight, BMI, waist circumference, WHR, percentage of fat and a modification of ghrelin was higher in patients undergoing controlled aerobic exercise against those with low-calorie diet (p = 0.004). Conclusions. Exercise appears to be a determining factor for the elevation of serum ghrelin. There is no significant relationship in the changes of serum ghrelin in relation to changes in BMI in both groups. Nor is there a relationship of ghrelin with the change in weight or body fat. Since in the greater 12 was the increase in ghrelin after diet the greater the decrease in weight, BMI and body fat.