Propiedades Nutracéuticas del Fruto de Cyrtocarpa procera Kunth

Abstract

Nutraceuticals are defined as those foods in addition to nutrient content; provide health benefits, containing substances that perform a specific action on the body's physiological functions. These substances can be antioxidants, phenolic compounds, phytosterols, fatty acids, or probiotics, which have been used by man to relieve various ailments such as respiratory diseases, wound healing, antiinflammatories to treat intestinal diseases among others. In our country, intestinal infectious diseases occupy a high morbidity, the vast majority of these infections are given by Gram-negative bacteria, which are a major health problem because resistant strains have arisen by misuse of drugs, so is now trying to synthesize new drugs that will eventually cause harm to humans, which is why alternatives have been sought in the use of natural products, a species used is the fruit of C. procera, better known as Chupandilla, besides being used as a food Antidiarrheal activity is attributed. Martínez Elizalde 2011 3 Therefore in this study was to determine the nutraceutical properties of the fruit of C. procera. The fruit was collected in the town of San Rafael, Coxcatlán (Puebla), the study was conducted bromatological (quantification of carbohydrates by the Nelson-Somogy method, lipids by Soxhlet method, protein by the Bradford method and Vitamin C, (by titration) of fresh fruit to assess their nutritional properties. then obtained methanol extract (M1) of the dried fruit of C. procera by the method of maceration. determined by the diffusion method of Kirby-Bauer antibacterial activity qualitatively and quantitatively by the broth microdilution method. We determined the bactericidal or bacteriostatic activity of the fruit of Chupandilla and cytotoxicity by the method of viability with crystal violet. The concentration of carbohydrates, lipids and proteins was 29, 1, 0.83%, respectively, and vitamin C was 0.44%, these results are within the parameters set for all the fruits in general. The carbohydrates that are present in the fruit are glucose, sucrose and fructose. The lipid content in the fruit is Vitamin E, squalene, campesterol, oleic acid and palmitic acid. The crude methanol extract (M1) and free of non-polar compounds (M2) showed antibacterial activity, the extract being the most active M2. The strains were sensitive to M2 V. cholerae Tor, S. aureus ATCC 29213, the MIC and MBC values ranging from 2 to 10 mg / mL. M1 and M2 extract are bacteriostatic, the median lethal dose (LC50) M1 and M2 both 14.86 and 22.03 is ug / mL, the antioxidant activity was 48.9 and 50 mg / mL respectively.