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dc.contributor.advisorDR. KORMANOVSKI KOVZOVA, ALEXANDRE-
dc.contributor.authorGODÍNEZ CEDILLO., JOSÉ OSCAR-
dc.date.accessioned2013-06-04T20:27:58Z-
dc.date.available2013-06-04T20:27:58Z-
dc.date.issued2011-02-01-
dc.identifier.urihttp://www.repositoriodigital.ipn.mx/handle/123456789/16286-
dc.descriptionEl trauma vascular y por ende el control de la hemorragia, han jugado un papel importante en la supervivencia de la humanidad. El manejo del trauma vascular ha evolucionado junto a la tecnología, pasando de la compresión, a la aplicación de agentes hemostáticos, ligadura vascular, reparación de lesiones y el uso de injertos, logrando así disminuir el porcentaje de amputaciones y mortalidad. La utilización de nuevos agentes hemostáticos externos puede ser usado para determinar la forma inicial del manejo así como de utilizar los recursos y la forma más adecuada de disminuir la mortalidad en pacientes que presentan hemorragias masivas secundarias a politrauma, ya que se disminuye el tiempo y la cantidad de la hemorragia y con ello se delimitan de una mejor forma las complicaciones de la misma. Se realizó un estudio farmacológico en ensayo clínico controlado en los hospitales de segundo nivel de la secretaría de Salud del Gobierno del Distrito Federal, en el servicio de urgencias, que tuvo como objetivo comparar la efectividad de un hemostático de uso externo del tipo de QuikClot, aplicándolo a otros pacientes en comparación con los hemostáticos tradicionales aplicados a otros pacientes, ambos grupos de pacientes con trauma vascular. Se encontró que los servicios de urgencias, alrededor del 70% de las consultas son de índole traumático y de las cuales el 40% presentan trauma vascular; los resultados reportaron que el trauma vascular se presenta con mayor frecuencia en el género masculino 75% siendo el grupo de edad más afectado entre los 18 y los 25 años de edad (35%), la región anatómica que con mayor frecuencia se lesiona son las extremidades en un 65%, siendo la hemorragia venosa la más frecuente en un 61%; con respecto al estado de choque con que se presentan los pacientes es el grado ll en un 43.3%. Con respecto a los hemostáticos se reportó que el QuikClot contuvo la hemorragia en un promedio de 3.07 minutos, ocasionando reacción exotérmica en un 60% de los pacientes, los hemostáticos convencionales lograron la hemostasia en un promedio de 23.6 min siendo el más utilizado la compresión directa en un 60%. Con estos datos se demuestra que el hemostático tipo Quikclot tiene mayor efectividad en el control de la hemorragia con respecto a los hemostáticos convencionales.es
dc.description.abstractVascular trauma and hence the control of bleeding, have played an important role in the survival of humanity, and is of necessity that mankind is able to develop various methods to control bleeding, using through history from the simple logic of compression, to the great advances today allow us to vascular repair through various methods that involve increasingly greater technological advances. The management of vascular trauma has evolved with technology and, ironically, the war has allowed to acquire knowledge and experience helping to advance, through compression, application of hemostatic agents, vascular ligation, repair of injuries and the use of grafts, achieving to decrease the percentage of amputations and mortality. The increase in the use of high speed transports, most urban violence, the high degree of industrialization and new diagnostic or therapeutic methods have contributed to the increased prevalence of vascular trauma. The use of new external hemostatic agents can be used to determine the initial shape of the management and use of resources and the most appropriate way of reducing mortality in patients with massive bleeding secondary to polytrauma, as it reduces the time and amount of bleeding and thereby define a better way complications thereof. We performed a pharmacological study in controlled clinical trials in the hospitals of second level of the Secretariat of Health of the Federal District, in the emergency department, which was intended to compare The hemostatic effectiveness of a type of external application of QuikClot, applying it to other patients in comparison with traditional hemostats applied to other patients, both groups of patients with vascular trauma. It was found that the emergency services, about 70% of the visits are traumatic in nature and which 40% have vascular trauma, there salts indicated that the vascular trauma occurs most frequently inthemale75% being most affected age group between 18 and 25 years of age (35%), the anatomical region most frequently injured were the extremities in 65%, being the most common venous bleeding by 61% compared to the state of shock presented to patients is the grade ll in 43.3%. With regard to the hemostatic QuikClot was reported that contained the bleeding by an average of 3.07 minutes, resulting exothermic reaction in 60% of patients, conventional hemostatic hemostasis achieved an average of 23.6 min being the most widely used direct compression by 60%. With this data shows that QuikClo the mostaticVascular trauma and hence the control of bleeding, have played an important role in the survival of humanity, and is of necessity that mankind is able to develop various methods to control bleeding, using through history from the simple logic of compression, to the great advances today allow us to vascular repair through various methods that involve increasingly greater technological advances. The management of vascular trauma has evolved with technology and, ironically, the war has allowed to acquire knowledge and experience helping to advance, through compression, application of hemostatic agents, vascular ligation, repair of injuries and the use of grafts, achieving to decrease the percentage of amputations and mortality. The increase in the use of high speed transports, most urban violence, the high degree of industrialization and new diagnostic or therapeutic methods have contributed to the increased prevalence of vascular trauma. The use of new external hemostatic agents can be used to determine the initial shape of the management and use of resources and the most appropriate way of reducing mortality in patients with massive bleeding secondary to polytrauma, as it reduces the time and amount of bleeding and thereby define a better way complications thereof. We performed a pharmacological study in controlled clinical trials in the hospitals of second level of the Secretariat of Health of the Federal District, in the emergency department, which was intended to compare The hemostatic effectiveness of a type of external application of QuikClot, applying it to other patients in comparison with traditional hemostats applied to other patients, both groups of patients with vascular trauma. It was found that the emergency services, about 70% of the visits are traumatic in nature and which 40% have vascular trauma, there salts indicated that the vascular trauma occurs most frequently inthemale75% being most affected age group between 18 and 25 years of age (35%), the anatomical region most frequently injured were the extremities in 65%, being the most common venous bleeding by 61% compared to the state of shock presented to patients is the grade ll in 43.3%. With regard to the hemostatic QuikClot was reported that contained the bleeding by an average of 3.07 minutes, resulting exothermic reaction in 60% of patients, conventional hemostatic hemostasis achieved an average of 23.6 min being the most widely used direct compression by 60%. With this data shows that QuikClo the mostatices
dc.language.isoeses
dc.subjectQuikClotes
dc.subjecttrauma vasculares
dc.subjectservicio de urgenciases
dc.titleEfectividad de QuikClot v.s. tratamiento tradicional en pacientes con trauma vascular del servicio de urgencias en hospitales de segundo niveles
dc.typeThesises
dc.description.especialidadESPECIALIDAD EN URGENCIAS MÉDICO QUIRÚRGICASes
dc.description.tipoPDFes
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