EFICACIA DE UN ESQUEMA SECUENCIAL VERSUS EL ESQUEMA TRADICIONAL PARA LA ERRADICACIÓN DE Helicobacter pylori EN NIÑOS Y ADUTOS EN MÉXICO.

Abstract

Background. Throughout the world the efficacy of treatment regimens used to eradicate Helicobacter pylori (Hp) has declined as a result of the resistance to the antibiotics used, the rates of eradication with schemes that initially high efficiency (80% or more ) are declining to 47% success rate. The clinicians have implemented multiple alternative schemes, one of the most efficient is called sequentially with success rates exceeding 90%. The work has been performed in Europe, particularly Italy which makes it essential to know the efficiency of this scheme in our population. Aims To evaluate the efficacy of sequential scheme versus the traditional in Hp eradication therapy in the Mexican population between 4 and 68 years of age. Material and methods: We conducted a clinical trial included children and adults between the ages of 4 and 68, assigned to one of two treatment groups for the eradication of Hp, "traditional or sequential scheme, 4 weeks after completion of treatment were assessed using a breath test to check the effectiveness of the treatment used. Results were collected from 40 patients of both sexes aged between 6 and 68. 18 patients with traditional treatment and the remaining 22 patients with sequential treatment breath test was positive for Hp infection in 5 of 18 (25%) patients with conservative treatment and 1 of 22 (5%) with sequential treatment effectiveness 95% versus 75% of standard treatment. with p <0.5, so that it can be concluded that sequential therapy is better than standard treatment.