Oxidative stress, cytoxicity, and cell mortality induced by nano-sized lead

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Campo DC	Valor	Lengua/Idioma
dc.creator	GUZMAN MENDOZA, JOSE	-
dc.date	2012-03-28T22:30:27Z	-
dc.date	2012-03-28T22:30:27Z	-
dc.date	2011-06-02	-
dc.date.accessioned	2013-01-16T15:28:32Z	-
dc.date.available	2013-01-16T15:28:32Z	-
dc.date.issued	2013-01-16	-
dc.identifier	CHEMOSPHERE, 84, 2011,1329 -1335	-
dc.identifier	http://hdl.handle.net/123456789/963	-
dc.identifier.uri	http://www.repositoriodigital.ipn.mx/handle/123456789/11443	-
dc.description	This paper reports on the effect of aqueous and nano-particulated Pb on oxidative stress (lipid peroxidation), cytoxicity, and cell mortality. As determined by the Thiobarbituric Acid Reactive Substances (TBARS) method, only 6 h after incubation aqueous suspensions bearing nano-sized PbO2, soluble Pb(II), and brain-homogenate only suspensions, were determined to contain as much as ca. 7, 5, and 1 nmol TBARS mg protein 1, respectively. Exposure of human cells (central nervous system, prostate, leukemia, colon, breast, lung cells) to nano-PbO2 led to cell-growth inhibition values (%) ca. 618.7%. Finally, as estimated by the Artemia salina test, cell mortality values were found to show high-survival larvae rates. Microscopic observations revealed that Pb particles were swallowed, but caused no mortality, however	-
dc.language	en_US	-
dc.publisher	ELSEVIER	-
dc.subject	LEAD	-
dc.subject	OXIDATIVE STRESS	-
dc.title	Oxidative stress, cytoxicity, and cell mortality induced by nano-sized lead	-
dc.type	Article	-
Aparece en las colecciones:	Doctorado

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